Monte-Carlo Expression Discovery

Performance comparison of four commercial GE discovery PET/CT scanners: A monte carlo study using GATE

  Combined PET/CT scanners now play a major role in medicine for in vivo imaging in oncology, cardiology, neurology, and psychiatry. As the performance of a scanner depends not only on the scintillating material but also on the scanner design, with regards to the advent of newer scanners, there is a need to optimize acquisition protocols as well as to compare scanner ...

Nested Monte-Carlo Expression Discovery

Nested Monte-Carlo search is a general algorithm that gives good results in single player games. Genetic Programming evaluates and combines trees to discover expressions that maximize a given evaluation function. In this paper Nested Monte-Carlo Search is used to generate expressions that are evaluated in the same way as in Genetic Programming. Single player Nested Monte-Carlo Search is transfo...

Monte Carlo Temperature Discovery Search for Combinatorial Games

A profile-based deterministic sequential Monte Carlo algorithm for motif discovery

MOTIVATION Conserved motifs often represent biological significance, providing insight on biological aspects such as gene transcription regulation, biomolecular secondary structure, presence of non-coding RNAs and evolution history. With the increasing number of sequenced genomic data, faster and more accurate tools are needed to automate the process of motif discovery. RESULTS We propose a d...

A Statistical Mechanical Approach to Combinatorial Chemistry

An analogy between combinatorial chemistry and Monte Carlo computer simulation is pursued. Examples of how to design libraries for both materials discovery and protein molecular evolution are given. For materials discovery, the concept of library redesign, or the use previous experiments to guide the design of new experiments, is introduced. For molecular evolution, examples of how to use ``bia...